Institute of Biological and Chemical Systems - Biological Information Processing

Karlsruhe Institute of Technology

Type of position: MPRO (F3) or Master Thesis (Biology)
Responsible PI / Contact: christine.blattner∂kit.edu
Title: How TRIM25 regulates cell proliferation and cell survival in prostate cancer.
 
Description: Recent transcriptomic analysis on the prostate cancer LNCaP cell line revealed the involvement of the E3 ubiquitin ligase TRIM25 in different pathways related to cell proliferation and apoptosis. During his/her internship in our laboratory, the student will use techniques of molecular biology to undercover the molecular mechanisms, through which TRIM25 regulates such cellular functions.