Chemical Screening Platforms

Semi-automated & higher-throughput
startle IBCS-BIP
Vibration Startle Response

Robust screening system for the evaluation of neuromuscular and general toxicity in zebrafish embryos

Publication
pmr IBCS-BIP
Photomotor Response

Zebrafish embryos react to the light pulse through activating the nervous system. This platform allows us to screen neuroactive chemicals.

Publication
touch IBCS-BIP
Touch Response

Confocal fluorescent microscopes

See deeper. Resolve finer. In 3D and beyond.
Zeiss LSM900 with Airyscan2

Fast and Gentle Confocal Super-Resolution for every colour.

dls IBCS-BIP
Leica DLS/SP8

Inverted DMi8 microscope with a lightsheet unit; Ex lasers: 405-nm, 488-nm; 561-nm; 633-nm; Hamamatsu Flash 4.0 V3 sCMOS camera; L10x/0.30 W DLS; L25x/0.95 W DLS; 10x/0.40; 20x/0.75 IMM; 40x/1.10 W; 63x/1.30 Glyc.

dive IBCS-BIP
Leica DIVE/SP8

2-photon laser (690-1040 nm); Upright microscope; 16x/0.6 IMM CORR VISIR, 20x/0.5 W, 40x/0.80 W, 63x/0.9 W; 4-Tune 3-channels (2x HyDs); 2x HyDs for internal detection; FALCON (FLIM).

Olympus spinning disc

4 lasers (405, 488, 561, 640-nm), Yokogawa W1 spinning disc, 2x Hamamatsu Orca Fusion, LED fluorescence, Piezo z-stage, temp. and CO2 incubator, water dispenser, software CellSense + ScanR, Available objectives:
UPlanXApo 4x/0.16 dry, UPlanXApo 10x/0.40 dry, UPlanXApo 20x/0.80 dry, UApoN340 20x/0.70 water, UPlanSApoIR 30x/1.05 silicone, UPlanXApo 40x/0.95 dry, UPlanApo 60x/1.50 oil,
UPlanSApo 60x/1.20 water, UPlanSApo 100x/1.35 silicone

Leica STED/SP8

Inverted microscope with a white light laser. Located in the basement of building 439. White light laser + 405 nm DMOD, 2x HyD, 20x/0.75 IMM, 40x/1.10 W, 93x/1.30 Glyc motC, STED 3X 775-nm; FALCON (FLIM).

Leica TCS SP5 (upright) & Leica TCS SP8 (inverted)

Wide-field fluorescent microscopes

Our workhorse for throughput
Leica Thunder Imager 1°

Inverted DMi8 microscope with environment controls

Leica Thunder Imager 2°

Upright DM6 microscope

slee IBCS-BIP
Leica DMi8

with colour camera

ix83 IBCS-BIP
Olympus IX83

PRIMO (micro-patterning) & luminescence imaging