Welcome to Our Premier Screening Center
Our facility is dedicated to leveraging innovative techniques to drive advancements in biological and biomedical research.
Through a combination of advanced tools and collaborative opportunities, we empower researchers to achieve groundbreaking discoveries and drive the future of biological science. Join us in exploring new dimensions of cellular research and discovering the full potential of our state-of-the-art capabilities.
FLUCS and Optofluidics: Interactive Microscopy
Discover the transformative techniques of focused-light-induced cytoplasmic streaming (FLUCS) and optofluidics. These methodologies make microscopy interactive, ensuring precise manipulation and assembly of cellular components. These advancements ensure that the right things happen to be at the right place at the right time.
New Readouts: The mechanics of nuclear sub-compartments
Explore how our cutting-edge method of optically induced chromatin deformation in living cells offers a new dimension in biological screening. This technique allows us to assess how compounds alter the physics and rheology of nuclear organization, providing unparalleled insights into cellular mechanics.
With High-Throughput Screens towards New Cell Functions
Understand the power of high-throughput microscopy and fluorescence-activated cell sorting (FACS). These technologies, combined with modern molecular perturbation techniques like CRISPR screens, enable us to gather extensive cellular data and explore new cell functions. This section highlights how these capabilities drive advancements in synthetic biology and directed evolution.
CRISPR and CRISPR Activation (CRISPRa) Screens
Learn about our innovative use of CRISPR and CRISPRa for genome-wide screens. This approach shifts from loss-of-function to gain-of-function phenotypes, providing a comprehensive understanding of gene functions and facilitating the development of novel therapeutic strategies. We focus on mammalian and human cell models to maximize biomedical relevance.
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Innovation Platform for New Technologies
Delve into our commitment to innovation with this section that highlights our role as an innovation platform. We develop new technologies for high-content screens, adding new dimensions of readout and capabilities at the interface of microscopy and microfluidics. By doing so, we connect back to our origins of pioneering technologies that have become standard assays in the scientific community.
